
    IN RE: NEXIUM (ESOMEPRAZOLE) PRODUCTS LIABILITY LITIGATION.
    MDL No. 2404.
    United States Judicial Panel on Multidistrict Litigation.
    Dec. 6, 2012.
    
      Before JOHN G. HEYBURN II, Chairman, W. ROYAL FURGESON, JR., PAUL J. BARBADORO, MARJORIE 0. RENDELL, CHARLES R. BREYER, and LEWIS A. KAPLAN, Judges of the Panel.
   TRANSFER ORDER

JOHN G. HEYBURN II, Chairman.

Before the Panel: Pursuant to 28 U.S.C. § 1407, plaintiffs in thirty-six actions pending in or originating in the Central District of California move to centralize this litigation in the Central District of California. This litigation currently consists of thirty-nine actions pending in nineteen district courts, as listed on Schedule A. The actions in this litigation involve products liability claims against. AstraZeneca arising from ingestion of the drug Nexium (esomeprazole magnesium), a proton pump inhibitor (PPI) prescribed for the treatment of heartburn, acid-reflux, and inflammation of the esophagus. Plaintiffs allege that Nexium may cause a variety of bone ailments — in particular, osteoporosis, loss of bone density, and bone fractures — and that AstraZeneca failed to adequately warn of these potential adverse side effects.

All the responding plaintiffs support centralization in the Central District of California. All of the responding defendants oppose centralization, but propose different alternative courses of action. AstraZeneca and McKesson alternatively suggest that, if this litigation is centralized, the Southern District of Texas should serve as the transferee district. Takeda alternatively requests the Panel separate and remand the claims against it in the Northern District of California Beatty action. Janssen, a defendant in a potential tag-along action, asks that we exclude that action from any centralized litigation.

In opposing centralization, defendants argue that each action will involve multiple individualized fact issues of causation and product identification that will require discovery unique to each case. Defendants also contend that any multidistrict litigation is destined to become an industry-wide litigation encompassing not only Nexium, but multiple different PPIs and manufacturers. We respectfully disagree.

Although defendants focus on product identification issues, we are not persuaded that these issues are so daunting that multidistrict treatment is unwarranted. Centralized products liability cases generally will involve some individual questions of fact. See In re Darvocet, Darvon & Propoxyphene Prods. Liab. Ditig., 780 F.Supp.2d 1379, 1381 (J.P.M.L. 2011). Section 1407 does not require a complete identity or even a majority of common factual issues as a prerequisite to centralization. Id. (citing cases). The transferee court can employ any number of pretrial techniques — such as establishing separate discovery and/or motion tracks — to manage this litigation efficiently-

Furthermore, experience has shown that pharmaceutical products liability actions do not inevitably expand to encompass all similar medications. Indeed, every plaintiff in each action on the motion alleges that he or she ingested Nexium and that this caused plaintiffs injuries. Actions that do not involve Nexium or do not contain allegations of bone-related injuries will not be centralized (barring an indication from the transferee court that the parameters of this litigation should be altered). Should the circumstances regarding any action develop such that either the transferee judge or the parties determine that continued inclusion of a claim or action no longer remains advisable, procedures are available whereby remand of that claim or action may be accomplished with a minimum of delay. See Panel Rule 10.1(b).

On the basis of the papers filed and the hearing session held, we find that these actions involve common questions of fact, and that centralization under Section 1407 in the Central District of California will serve the convenience of the parties and witnesses and promote the just and efficient conduct of this litigation. All the actions before the Panel assert claims against AstraZeneca arising from ingestion of the drug Nexium. Specifically, the actions share allegations relating to the safety of Nexium and the adequacy of AstraZeneca’s warnings concerning the possible adverse side effects of using Nexium — in particular, the potential that Nexium may cause bone-related injuries such as osteoporosis, bone deterioration or loss, and broken bones. Centralization will eliminate duplicative discovery; prevent inconsistent pretrial rulings; and conserve the resources of the parties, their counsel and the judiciary.

We decline Takeda’s alternative request to separate and remand the Northern District of California Beatty action from this litigation. That request is based on the allegation of one plaintiff in that action that she ingested both Takeda’s Prevacid and AstraZeneca’s Nexium. Excluding the claims against Takeda will result only in duplicative discovery and pretrial practice. The transferee judge can structure the pretrial proceedings so that discovery with respect to any issues unique to Takeda can proceed concurrently with discovery on common issues. See In re Coloplast Corp. Pelvic Support Sys. Prods. Liab. Litig., 883 F.Supp.2d 1348, 1348-49 (J.P.M.L.2012).

Normally, we would consider Janssen’s request to exclude the potentially-related Goodman action in the District of Nevada from the MDL to be premature. See In re DePuy Orthopaedics, Inc., Pinnacle Hip Implant Prods. Liab. Litig., 787 F.Supp.2d 1358, 1360 (J.P.M.L.2011). However, based on the injury described in the complaint (hypomagnesemia) and the parties’ arguments, it is apparent that Goodman does not fall within the scope of this MDL. Accordingly, we will not conditionally transfer that action to the MDL. If any involved party believes that Goodman should be centralized, it may file a separate motion to that effect. See Panel Rule 7.1(b)®.

We conclude that the Central District of California is an appropriate transferee district for this litigation. The eight actions pending in that district involve the vast majority of plaintiffs in this litigation — over a thousand plaintiffs. Further, twenty-eight of the non-California actions were initially transferred from the Central District of California pursuant to 28 U.S.C. § 1404. The Central District of California is also accessible and is proximate to at least four state court actions involving approximately another two hundred plaintiffs. Thus, centralization in this district will facilitate coordination with pending state court litigation. Finally, by selecting Judge Dale S. Fischer to preside over this matter, we are selecting a jurist with multidistrict litigation experience and the ability to handle this litigation.

IT IS THEREFORE ORDERED that, pursuant to 28 U.S.C. § 1407, the actions listed on Schedule A and pending outside the Central District of California are transferred to the Central District of California and, with the consent of that court, assigned to the Honorable Dale S. Fischer for coordinated or consolidated pretrial proceedings with the actions pending there.

SCHEDULE A

MDL No. 2404 — IN RE: NEXIUM (ESOMEPRAZOLE) PRODUCTS LIABILITY LITIGATION

Central District of California

Linda Carrasco, et al. v. McKesson Corporation, et al., C.A. No. 2:12-05044

Lupe Abina, et al. v. McKesson Corporation, et al., C.A. No. 2:12-05046

Antoinette Johnson, et al. v. McKesson Corporation, et al., C.A. No. 2:12-05048

Unniebe Solomon, et al. v. McKesson Corporation, et al., C.A. No. 2:12-05049

Pamela Mason, et al. v. McKesson Corporation, et al., C.A. No. 2:12-05050

Christine Nickerson, et al. v. McKesson Corporation, et al., C.A. No. 2:12-05052

Sherwin Arae, et al. v. McKesson Corporation, et al., C.A. No. 2:12-05053

Phyllis Cudney, et al. v. McKesson Corporation, et al., C.A. No. 2:12-05077

Northern District of California

Judy Beatty, et al. v. AstraZeneca Pharmaceuticals, L.P., et al., C.A. No. 4:12-03507

Southern District of California

Lois Hornsby, et al. v. AstraZeneca Pharmaceuticals LP, et al., C.A. No. 3:12-01307

Eastern District of Tennessee

Georgia Lou Payne v. McKesson Corporation, et al., C.A. No. 3:12-00341

Rodney Penland v. McKesson Corporation, et al., C.A. No. 3:12-00342

Cynthia Phillips v. McKesson Corporation, et al., C.A. No. 3:12-00343

Kelly Wayne Powers v. McKesson Corporation, et al., C.A. No. 3:12-00344

Peggy Smith v. McKesson Corporation, et al., C.A. No. 3:12-00345

Debra Ann Sweet v. McKesson Corporation, et al., C.A. No. 3:12-00346

Daniel Robin Thomas v. McKesson Corporation, et al., C.A. No. 3:12-00347

Kelly Toler-Alien v. McKesson Corporation, et al., C.A. No. 3:12-00348

Mary Ann Wheeler v. McKesson Corporation, et al., C.A. No. 3:12-00349

Middle District of Tennessee

James R. Biggers, et al. v. AstraZeneca, LP, et al., C.A. No. 1:11-00062

Western District of Tennessee

Beatrice Velasco, et al. v. McKesson Corporation, et al., C.A. No. 2:12-02613

Eastern District of Texas

Beatrice Velasco, et al. v. McKesson Corporation, et al., C.A. No. 6:12-00444

Northern District of Texas

Beatrice Velasco, et al. v. McKesson Corporation, et al., C.A. No. 3:12-02241

Southern District of Texas

Beatrice Velasco, et al. v. McKesson Corporation, et al., C.A. No. 4:12-02099

Western District of Texas

Irene Avelar, et al. v. McKesson Corporation, et al., C.A. No. 5:12-00673

District of Utah

Wendy Collins, et al. v. McKesson Corporation, et al., C.A. No. 2:12-00687

Eastern District of Virginia

Kraig Jackson, et al. v. McKesson Corporation, et al., C.A. No. 2:12-00401

Western District of Virginia

Shirley Bradley, et al. v. McKesson Corporation, et al., C.A. No. 7:12-00304

Western District of Washington

Beatrice Velasco, et al. v. McKesson Corporation, et al., C.A. No. 2:12-01208

Northern District of West Virginia

Jody Schnaak v. McKesson Corporation, et al., C.A. No. 1:12-00111

Betty Conner v. McKesson Corporation, et al., C.A. No. 2:12-00049

Patricia DeLorenzo v. McKesson Corporation, et al., C.A. No. 5:12-00106

Paul Whitlatch v. McKesson Corporation, et al., C.A. No. 5:12-00107

Southern District of West Virginia

Dawn Johnson, et al. v. McKesson Corporation, et al., C.A. No. 2:12-03054

Eastern District of Wisconsin

Emma Kuhn v. McKesson Corporation, et al., C.A. No. 2:12-00717

John McMahon v. McKesson Corporation, et al., C.A. No. 2:12-00718

Latrisha Morrow v. McKesson Corporation, et al., C.A. No. 2:12-00719

Western District of Wisconsin

Barbara Moore v. McKesson Corporation, et al., C.A. No. 3:12-00496

District of Wyoming

Juanita Kaye Westlake v. McKesson Corporation, et al., C.A. No. 2:12-00152 
      
       Judge Kathryn H. Vratil took no part in the decision of this matter.
     
      
      . The parties have notified the Panel of three additional related actions pending in the Northern District of Alabama, the Northern District of Illinois, and the District of Nevada (a fourth potentially related action was subsequently dismissed). These actions and any other related actions are potential tag-along actions. See Panel Rule 7.1.
     
      
      . The responding defendants are: AstraZeneca Pharmaceuticals LP and AstraZeneca LP (AstraZeneca); McKesson Corporation (McKesson); Takeda Pharmaceuticals U.S.A., Inc., Takeda Global Research & Development Center, Inc., Takeda Pharmaceuticals International, Inc., Takeda America Holdings, Inc., and Takeda California, Inc. f/k/a Takeda San Diego, Inc. (Takeda); and Johnson & Johnson and Janssen Pharmaceuticals, Inc. (Janssen).
     
      
      . As we have previously observed, the considerations affecting transfer under Section 1404 are not the same as those affecting transfer under Section 1407, and there is no inconsistency in centralizing actions that have been so transferred in the originating district. See In re Epogen & Aranesp Off-Label Mktg. & Sales Practices Litig., 545 F.Supp.2d 1365, 1367 (J.P.M.L.2008).
     